Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL

LigandBDBM50307552(1-Methyl-8-[(pyridin-3-ylmethyl)amino]-4,5-dihydro...)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL

LigandBDBM50307552(1-Methyl-8-[(pyridin-3-ylmethyl)amino]-4,5-dihydro...)Copy SMILESCopy InChI

Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI