Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Fidelta

Curated by ChEMBL

LigandBDBM50438921(CHEMBL1394266)Copy SMILESCopy InChI

Affinity DataIC50:  29nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL

LigandBDBM50438921(CHEMBL1394266)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of APE-1 (unknown origin) using double-stranded AP-site containing DNA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL

LigandBDBM50438921(CHEMBL1394266)Copy SMILESCopy InChI

Affinity DataEC50:  960nMAssay Description:Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate after 60 minsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI