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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
hit in this display
Target
Mitogen-activated protein kinase 1 [8-360]
(Homo sapiens (Human))
Array Biopharma
US Patent
Ligand
BDBM193675
(US9670208, Example 279 N-(1-methyl-1H-pyrazol-5-yl...)
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Affinity Data
IC50: 0.600nM
pH: 7.3
Assay Description:
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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