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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50099268
(2-Cyclohexyl-6-fluoro-3-(4-fluoro-piperidin-3-yl)-...)
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Affinity Data
Ki: 0.25nM
Assay Description:
Ability to displace [3H]-ketanserin binding to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50099268
(2-Cyclohexyl-6-fluoro-3-(4-fluoro-piperidin-3-yl)-...)
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Affinity Data
Ki: 5nM
Assay Description:
Ability to displace [3H]-mesulergine binding to human 5-hydroxytryptamine 2C receptor stably expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50099268
(2-Cyclohexyl-6-fluoro-3-(4-fluoro-piperidin-3-yl)-...)
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Affinity Data
Ki: >1.60E+3nM
Assay Description:
Ability to displace [3H]-spiperone binding to CHO cells stably expressing dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50099268
(2-Cyclohexyl-6-fluoro-3-(4-fluoro-piperidin-3-yl)-...)
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Affinity Data
Ki: 5.40E+3nM
Assay Description:
Inhibition of human ERG channel
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50099268
(2-Cyclohexyl-6-fluoro-3-(4-fluoro-piperidin-3-yl)-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.40E+3nM
Assay Description:
Displacement of [3H]-dofetilide from HEK cells expressing hERG voltage dependent IKr potassium channel Kv11.1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI