Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMelatonin receptor type 1A/1B(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL

LigandBDBM50118442(2,2,2-Trifluoro-N-(2-indan-1-yl-ethyl)-acetamide |...)Copy SMILESCopy InChI

Affinity DataKi:  12nMAssay Description:Ability to inhibit 2-[125I]iodomelatonin specific binding to human melatonin receptor type 1A (MT1) expressed in CHO cells.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL

LigandBDBM50118442(2,2,2-Trifluoro-N-(2-indan-1-yl-ethyl)-acetamide |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit 2-[125I]iodomelatonin specific binding to melatonin receptor 3 (MT3) of Syrian hamster brain.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI