Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetMonoglyceride lipase(Mus musculus (mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280568(US10030020, Example 113 | US10781211, Example 113)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Mus musculus (mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280568(US10030020, Example 113 | US10781211, Example 113)
Affinity DataIC50: <100nMAssay Description:MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM280568(US10030020, Example 113 | US10781211, Example 113)
Affinity DataIC50: >1.00E+3nMAssay Description:MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM280568(US10030020, Example 113 | US10781211, Example 113)
Affinity DataIC50: >1.00E+3nMAssay Description:MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM280568(US10030020, Example 113 | US10781211, Example 113)
Affinity DataIC50: >1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD2(Mus musculus (Mouse))
Abide Therapeutics

US Patent
LigandPNGBDBM280568(US10030020, Example 113 | US10781211, Example 113)
Affinity DataIC50: >1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent