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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Androgen receptor
(Homo sapiens (Human))
Ligand Pharmaceuticals
Ligand
BDBM18198
(1-(cyclopropylmethyl)-9-(trifluoromethyl)-1H,2H,3H...)
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Affinity Data
Ki: 1.60nM ΔG°: -52.2kJ/mole EC50: 1.40nM
pH: 7.4 T: 2°C
Assay Description:
The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Progesterone receptor
(Homo sapiens (Human))
Ligand Pharmaceuticals
Ligand
BDBM18198
(1-(cyclopropylmethyl)-9-(trifluoromethyl)-1H,2H,3H...)
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Affinity Data
Ki: 2.00E+3nM ΔG°: -30.2kJ/mole
pH: 7.4 T: 2°C
Assay Description:
The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Ligand Pharmaceuticals
Ligand
BDBM18198
(1-(cyclopropylmethyl)-9-(trifluoromethyl)-1H,2H,3H...)
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Affinity Data
Ki: 8.80E+3nM ΔG°: -26.8kJ/mole
pH: 7.4 T: 2°C
Assay Description:
The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI