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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by
ChEMBL
Ligand
BDBM50170223
(CHEMBL3805330)
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Affinity Data
IC50: 8nM
Assay Description:
Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by
ChEMBL
Ligand
BDBM50170223
(CHEMBL3805330)
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Affinity Data
IC50: 100nM
Assay Description:
Inhibition of full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) T315I mutant expressed in baculovirus expression system us...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by
ChEMBL
Ligand
BDBM50170223
(CHEMBL3805330)
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Affinity Data
IC50: 210nM
Assay Description:
Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by
ChEMBL
Ligand
BDBM50170223
(CHEMBL3805330)
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Copy InChI
Affinity Data
IC50: 510nM
Assay Description:
Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by
ChEMBL
Ligand
BDBM50170223
(CHEMBL3805330)
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Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Experimental Therapeutics Centre
Curated by
ChEMBL
Ligand
BDBM50170223
(CHEMBL3805330)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI