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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50193699
(CHEMBL215662 | N-(2-(piperidin-1-yl)quinolin-6-yl)...)
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Affinity Data
IC50: 12nM
Assay Description:
Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanin-concentrating hormone receptor 1
(RAT)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50193699
(CHEMBL215662 | N-(2-(piperidin-1-yl)quinolin-6-yl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 110nM
Assay Description:
Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI