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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM92663(C7-substituted chromone derivative, 3n)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human MAO-B expressed in insect cell microsomes using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM92663(C7-substituted chromone derivative, 3n)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:Inhibition studies using recombinant human MAO-A and MAO-B that were obtained from commercial sources (Sigma-Aldrich).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM92663(C7-substituted chromone derivative, 3n)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

LigandPNGBDBM92663(C7-substituted chromone derivative, 3n)
Affinity DataIC50:  1.97E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition studies using recombinant human MAO-A and MAO-B that were obtained from commercial sources (Sigma-Aldrich).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

LigandPNGBDBM92663(C7-substituted chromone derivative, 3n)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in insect cell microsomes using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

LigandPNGBDBM92663(C7-substituted chromone derivative, 3n)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed