Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297620(1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-(...)
Affinity DataIC50:  38nMAssay Description:Displacement of [125I]MCH from human MCH1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297620(1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-(...)
Affinity DataIC50:  570nMAssay Description:Inhibition of human recombinant CYP3A4 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50297620(1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-(...)
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed