Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 17 hits in this display   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50:  580nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9 by P450-Glo methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19 by P450-Glo methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 by P450-Glo methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of dopamine D3 (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5HT1A (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5HT2A (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5HT2C (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5HT6 (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5HT7 (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of dopamine D2 (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 by P450-Glo methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of dopamine D4 (receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315024((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 by P450-Glo methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed