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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
C-C chemokine receptor type 2
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: 23nM
Assay Description:
Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet staining
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
C-C chemokine receptor type 2
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: 30nM
Assay Description:
Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium level
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
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Article
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Target
C-C chemokine receptor type 2
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: 580nM
Assay Description:
Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP2C9 by P450-Glo method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP2C19 by P450-Glo method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
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Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP2D6 by P450-Glo method
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of dopamine D3 (receptor)
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of 5HT1A (receptor)
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of 5HT2A (receptor)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of 5HT2C (receptor)
More data for this Ligand-Target Pair
Target Info
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KEGG
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Article
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of 5HT6 (receptor)
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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CHEMBL
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of 5HT7 (receptor)
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of dopamine D2 (receptor)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP1A2 by P450-Glo method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
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Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of [3H]astemizole from human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
D(4) dopamine receptor
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of dopamine D4 (receptor)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Yangji Chemicals
Curated by
ChEMBL
Ligand
BDBM50315024
((R)-N-(2-(1-(2-(1-benzoylpiperidin-4-yl)ethyl)pyrr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP3A4 by P450-Glo method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI