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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Acyl-CoA desaturase 1
(Mus musculus)
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50306128
(1-(pyridin-3-ylmethyl)-3-(6-(5-(trifluoromethyl)sp...)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of SCD1 in mouse microsomal liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Stearoyl-CoA desaturase
(Homo sapiens (Human))
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50306128
(1-(pyridin-3-ylmethyl)-3-(6-(5-(trifluoromethyl)sp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fraction
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stearoyl-CoA desaturase
(Homo sapiens (Human))
Daiichi Sankyo
Curated by
ChEMBL
Ligand
BDBM50306128
(1-(pyridin-3-ylmethyl)-3-(6-(5-(trifluoromethyl)sp...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 106nM
Assay Description:
Inhibition of human SCD1 expressed in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI