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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
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Affinity Data
Ki: 0.830nM
Assay Description:
Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysis
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Binding affinity to 5-HT6R (unknown origin) assessed as inhibition constant
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter method
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 6
(RAT)
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
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Affinity Data
Ki: 0.830nM
Assay Description:
Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptor
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 6
(RAT)
Jagiellonian University Medical College
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptor
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Binding affinity to 5HT6R (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MCE
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Antagonist activity at 5-HT6 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
Assay Description:
Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.830nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.5nM
Assay Description:
Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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MCE
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.90nM
Assay Description:
Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membrane measured after 60 mins
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
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Affinity Data
Ki: 250nM
Assay Description:
Displacement of [3H]5-HT from 5-HT2C receptor (unknown origin) expressed in hamster AV12 cells
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
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Affinity Data
Ki: 791nM
Assay Description:
Binding affinity to human 5-HT2AR expressed in HEK293 cells by competitive binding assay
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
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Affinity Data
Ki: 1.22E+3nM
Assay Description:
Displacement of [3H]-raclopride from human D2R expressed in HEK293 cells after 1 hr by microbeta plate reader analysis
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
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Affinity Data
Ki: 3.94E+3nM
Assay Description:
Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by microbeta plate reader analysis
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
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Affinity Data
Ki: 8.64E+3nM
Assay Description:
Displacement of [3H]-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by microbeta plate reader analysis
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Antagonist activity at recombinant human 5HT6R expressed in CHO cells assessed as inhibition of 5HT-stimulated cAMP accumulation incubated for 4 hrs ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
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MCE
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PC sid
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In Depth
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PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50019754
(IDALOPIRDINE | LU-AE58054)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Antagonist activity at human 5HT6 receptor expressed in COS-7 cells assessed as inhibition of 5HT-induced cAMP accumulation preincubated for 7 mins f...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MCE
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI