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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM174331
(US9688669, Example 121)
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Affinity Data
Ki: 200nM
Assay Description:
Displacement of [3H]MPEPy from human mGluR5 expressed in cell membranes after 60 mins by liquid scintillation counting method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Isoform 1 of Metabotropic glutamate receptor 5 (5a)
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM174331
(US9688669, Example 121)
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Affinity Data
EC50: 18nM
Assay Description:
HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM174331
(US9688669, Example 121)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18nM
Assay Description:
Positive allosteric modulation activity at human mGluR5A expressed in HEK293(ZF) cells co-expressing rat glutamate-aspartate transporter assessed as ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI