Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL

LigandBDBM50215799(2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl...)Copy SMILESCopy InChI

Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL

LigandBDBM50215799(2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl...)Copy SMILESCopy InChI

Affinity DataIC50:  146nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI