Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50343270(7-(4-(4-(3-chloro-2-fluorophenyl)piperazin-1-yl)bu...)Copy SMILESCopy InChI

Affinity DataKi:  1nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50343270(7-(4-(4-(3-chloro-2-fluorophenyl)piperazin-1-yl)bu...)Copy SMILESCopy InChI

Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50343270(7-(4-(4-(3-chloro-2-fluorophenyl)piperazin-1-yl)bu...)Copy SMILESCopy InChI

Affinity DataKi:  10.4nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI