Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50442608(CHEMBL2441420)Copy SMILESCopy InChI

Affinity DataIC50:  38nMAssay Description:Inhibition of human ROMK channel by electrophysiology assayMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50442608(CHEMBL2441420)Copy SMILESCopy InChI

Affinity DataIC50:  110nMAssay Description:Inhibition of human ROMK channel-mediated 86Rb+ flux expressed in CHO cells after 35 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI