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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Aldo-keto reductase family 1 member B1 [K65Q]
(Bos taurus (Cattle))
Wyeth-Ayerst Research
Curated by
ChEMBL
Ligand
BDBM50038840
((4R)-2-[(4-bromo-2-fluorophenyl)methyl]-2,3-dihydr...)
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Affinity Data
IC50: 10nM
Assay Description:
In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
Wyeth-Ayerst Research
Curated by
ChEMBL
Ligand
BDBM50038839
(2-(4-bromo-2-fluorobenzyl)-1H,2'H,5'H-spiro[isoqui...)
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Affinity Data
IC50: 19nM
Assay Description:
Compound was evaluated In vitro for inhibition of aldose reductase activity by 50% in dog RBC
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1 [K65Q]
(Bos taurus (Cattle))
Wyeth-Ayerst Research
Curated by
ChEMBL
Ligand
BDBM50038839
(2-(4-bromo-2-fluorobenzyl)-1H,2'H,5'H-spiro[isoqui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1 [K65Q]
(Bos taurus (Cattle))
Wyeth-Ayerst Research
Curated by
ChEMBL
Ligand
BDBM50038839
(2-(4-bromo-2-fluorobenzyl)-1H,2'H,5'H-spiro[isoqui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Compound was tested in vitro for inhibition of aldose reductase activity in partially purified bovine lens preparation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aldo-keto reductase family 1 member B1 [K65Q]
(Bos taurus (Cattle))
Wyeth-Ayerst Research
Curated by
ChEMBL
Ligand
BDBM50038850
((4S)-2-[(4-bromo-2-fluorophenyl)methyl]-2,3-dihydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparation
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI