Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent

LigandBDBM141852(US8921410, Table 1 Compound 15)Copy SMILESCopy InChI

Affinity DataKi:  24nM ΔG°:  -42.9kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent

LigandBDBM141852(US8921410, Table 1 Compound 15)Copy SMILESCopy InChI

Affinity DataKi:  54nM ΔG°:  -40.9kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI