Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

LigandBDBM50420362(CHEMBL2089182)Copy SMILESCopy InChI

Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]MPEP from mGluR5 in Sprague-Dawley rat brain membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

LigandBDBM50420362(CHEMBL2089182)Copy SMILESCopy InChI

Affinity DataIC50:  9nMAssay Description:Inverse agonist activity at rat mGluR5 expressed in HEK293A cells coexpressing Gqalpha assessed as inhibition of quisqualic-induced D-myo-inositol 1 ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI