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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Mitogen-activated protein kinase 14
(Mus musculus (mouse))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50122918
(2-(2,6-Dichloro-phenyl)-6-[2-(2,4-difluoro-phenyl)...)
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Affinity Data
IC50: 22nM
Assay Description:
Tested in vitro for filter plate binding versus gamma-[33P]ATP in active recombinant murine FLAG-P38 alpha fusion protein (GST-Activating transcripti...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Mitogen-activated protein kinase 11
(Mus musculus (mouse))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50122918
(2-(2,6-Dichloro-phenyl)-6-[2-(2,4-difluoro-phenyl)...)
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Affinity Data
IC50: 112nM
Assay Description:
Displacement of [gamma-33P]-ATP binding from active recombinant murine FLAG-Mitogen-activated protein kinase p38 beta fusion protein (GST-ATF2)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50122918
(2-(2,6-Dichloro-phenyl)-6-[2-(2,4-difluoro-phenyl)...)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of LPS-induced p38-related Tumor necrosis factor alpha release in human whole blood
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI