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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Affinity Data
IC50: <100nM
pH: 7.5 T: 2°C
Assay Description:
In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Affinity Data
IC50: <100nM
pH: 7.5
Assay Description:
In one assay the biochemical activity IC50 values are determined with respect to inhibition of c-Kit kinase activity, where inhibition of phosphoryla...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Affinity Data
IC50: <100nM
pH: 7.5 T: 2°C
Assay Description:
In one assay the biochemical activity IC50 values are determined with respect to inhibition of Flt-3 kinase activity, where inhibition of phosphoryla...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Affinity Data
IC50: <5.00E+3nM
Assay Description:
CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Copy InChI
Affinity Data
IC50: 5.00E+3nM
Assay Description:
CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
Copy SMILES
Copy InChI
Affinity Data
IC50: <5.00E+3nM
Assay Description:
CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Plexxikon
US Patent
Ligand
BDBM174966
(US9096593, P-2004)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
CYP (Cytochrome P450) enzymes are the major drug metabolizing enzymes present in the liver. The inhibition of CYP enzyme activity (IC50) for each of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI