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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Syntrix Biosystems
Curated by
ChEMBL
Ligand
BDBM150821
(US8981106, 12)
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Affinity Data
IC50: 390nM
Assay Description:
Antagonist activity at CXCR2 in human PMNs assessed as inhibition of CXCL1-induced intracellular Ca2+ release by fluorescence based calcium flux assa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Syntrix Biosystems
Curated by
ChEMBL
Ligand
BDBM150821
(US8981106, 12)
Copy SMILES
Copy InChI
Affinity Data
IC50: 393nM
T: 2°C
Assay Description:
An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI