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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAromatase(Homo sapiens (Human))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339655(7-(3,4-Difluorophenoxy)-4-(1H-imidazol-1-ylmethyl)...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339655(7-(3,4-Difluorophenoxy)-4-(1H-imidazol-1-ylmethyl)...)
Affinity DataIC50:  933nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` Degli Studi Di Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50339655(7-(3,4-Difluorophenoxy)-4-(1H-imidazol-1-ylmethyl)...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed