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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Glucagon receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50075753
(4-[3,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyrid...)
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Affinity Data
IC50: 90nM
Assay Description:
Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50075753
(4-[3,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyrid...)
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Copy InChI
Affinity Data
IC50: 340nM
Assay Description:
Inhibitory activity against p38-alpha kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucagon receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50075753
(4-[3,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyrid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 340nM
Assay Description:
Antagonist activity at human glucagon receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Glucagon receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50075753
(4-[3,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyrid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 350nM
Assay Description:
Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucagon receptor
(Mus musculus)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50075753
(4-[3,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyrid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 430nM
Assay Description:
Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucagon receptor
(Mus musculus)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50075753
(4-[3,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyrid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+3nM
Assay Description:
Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI