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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264740(4-(4'-fluorobiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl)...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264740(4-(4'-fluorobiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl)...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of COT (unknown origin) by cell-based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264740(4-(4'-fluorobiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl)...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of MEK1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed