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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50258330
(2-(4-Fluorophenyl)-5-(6-methylpyridin-2-ylethynyl)...)
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Affinity Data
Ki: 3nM
Assay Description:
Displacement of [3H]MPEP from rat brain recombinant mGluR5 expressed in HEK293T cells by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50258330
(2-(4-Fluorophenyl)-5-(6-methylpyridin-2-ylethynyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.20nM
Assay Description:
Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as glutamate-induced calcium flux preincubated for 140 sec before glutamate cha...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI