Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Pfizer
Ligand
BDBM84801
(PF-00416121)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
pH: 7.5 T: 2°C
Assay Description:
Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human))
University Of Zagreb
Curated by
ChEMBL
Ligand
BDBM84801
(PF-00416121)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of MAPK p38 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Pfizer
Ligand
BDBM84801
(PF-00416121)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.25E+4nM
pH: 7.5 T: 2°C
Assay Description:
Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI