Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50:  12.6nMAssay Description:Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50:  100nMAssay Description:Activity at GR in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50:  2.51E+3nMAssay Description:Binding affinity to ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to PRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416101(CHEMBL1082780)
Affinity DataEC50:  251nMAssay Description:Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed