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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]-Ketanserin from rat frontal cortex 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Mainz

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]altanserine from rat cortical membrane 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Mainz

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyserMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-WB4101 from rat forebrain alpha 1 adrenergic receptorsMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  40nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin) by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  62nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin) by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-halopridol from rat striatum D2 receptorsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  71nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  280nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(RAT)
Janssen Pharmaceutica

Curated by PDSP Ki Database
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  290nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  1.57E+3nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) by competitive binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Mainz

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at recombinant human 5-HT2A expressed in human U2OS cells by pathhunter beta-arrestin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed