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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50443353(CHEMBL3086036 | US8669252, 14)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50443353(CHEMBL3086036 | US8669252, 14)
Affinity DataIC50:  1.40nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50443353(CHEMBL3086036 | US8669252, 14)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed