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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
5-hydroxytryptamine receptor 1A/1B/1D/1F
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50280818
(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
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Affinity Data
IC50: 12nM
Assay Description:
Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
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Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50280818
(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
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Affinity Data
IC50: >100nM
Assay Description:
Tested for its binding affinity against muscarinic receptor; showed no appreciable affinity at concentration specified
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50280818
(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
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Affinity Data
IC50: >100nM
Assay Description:
Tested for its binding affinity against Alpha-1 adrenergic receptor; showed no appreciable affinity at concentration specified
More data for this Ligand-Target Pair
Target Info
MMDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(2) dopamine receptor
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50280818
(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
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Copy InChI
Affinity Data
IC50: >100nM
Assay Description:
Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specified
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI