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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6nM
Assay Description:
Displacement of labeled paroxetine from 5-HT transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6nM
Assay Description:
Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6nM
Assay Description:
Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8nM
Assay Description:
Displacement of [3H]OH-DPAP from human 5HT1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Displacement of labeled paroxetine from 5-HT transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Displacement of labeled paroxetine from 5-HT transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 223nM
Assay Description:
Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activity
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 223nM
Assay Description:
Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activity
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50305106
((+)-8-((cyclopropylmethyl)(3-(5-fluoro-1H-indol-3-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 24nM
Assay Description:
Agonist activity at human 5HT1A receptor expressed in CHO cells assessed as inhibition of forskolin-induced adenylate cyclase activity
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI