Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 21 hits in this display   

TargetTyrosine-protein kinase(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  598nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  655nMAssay Description:Inhibition of CYP2D6 using dextromethorphan as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of MerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of AxlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Gsk3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MAPKAP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Pim-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360611(CHEMBL1933550)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PKCzetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed