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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50065421
(3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piper...)
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Affinity Data
IC50: 0.700nM
Assay Description:
Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50065421
(3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.75nM
Assay Description:
Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50065421
(3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Displacement of specific [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1B receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50065421
(3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piper...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5nM
Assay Description:
Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1D receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50065421
(3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piper...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5.10nM
Assay Description:
Agonist induced [35S]-GTP-gammaS, binding in CHO cells expressing 5-HT 1d receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50065421
(3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piper...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 440nM
Assay Description:
Agonist-induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with human 5-hydroxytryptamine 1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI