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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)
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Affinity Data
Ki: 16nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)
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Affinity Data
Ki: 94nM
Assay Description:
Displacement of [3H]citalopram from human SERT by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)
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Affinity Data
Ki: 312nM
Assay Description:
Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)
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Affinity Data
Ki: 374nM
Assay Description:
Displacement of [3H]nisoxetine from human NET by scintillation proximity assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI