Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
Beta-glucuronidase(Escherichia coli (Enterobacteria))University Of North Carolina At Chapel Hill
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Beta-galactosidase(Streptococcus agalactiae (Firmicutes))University Of North Carolina At Chapel Hill
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Ki: 2.80E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Ki: 6.10E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Beta-glucuronidase(Homo sapiens (Human))University Of North Carolina At Chapel Hill
US Patent
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Beta-glucuronidase(Homo sapiens (Human))University Of North Carolina At Chapel Hill
US Patent
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Beta-glucuronidase(Homo sapiens (Human))University Of North Carolina At Chapel Hill
US Patent
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Beta-glucuronidase(Homo sapiens (Human))University Of North Carolina At Chapel Hill
US Patent
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
EC50: 811nMAssay Description:PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair
Beta-glucuronidase(Homo sapiens (Human))University Of North Carolina At Chapel Hill
US Patent
BDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
EC50: 913nMAssay Description:PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair