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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Metabotropic glutamate receptor 1
(RAT)
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50258227
(4,5-difluoro-N-(4-(trifluoromethyl)oxazol-2-yl)-9H...)
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Affinity Data
EC50: 47nM
Assay Description:
Agonist activity at rat mGlu1 receptor expressed in HEK293 cells assessed as increase in intracellular calcium by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 1
(RAT)
F. Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50258227
(4,5-difluoro-N-(4-(trifluoromethyl)oxazol-2-yl)-9H...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 161nM
Assay Description:
Agonist activity at rat mGlu1 receptor expressed in CHO cells assessed as reversal of glutamate-activated K+ currents by electrophysiology
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI