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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  21nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  240nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of GST-tagged human recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF20A(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF20A(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140932(CHEMBL3753668)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed