Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK4
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 130nM
Assay Description:
Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 240nM
Assay Description:
Inhibition of GST-tagged human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.60E+3nM
Assay Description:
Inhibition of GST-tagged human recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK3
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of GST-tagged human recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kinesin-like protein KIF20A
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.02E+4nM
Assay Description:
Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kinesin-like protein KIF20A
(Homo sapiens (Human))
Cnrs
Curated by
ChEMBL
Ligand
BDBM50140932
(CHEMBL3753668)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI