Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL

LigandBDBM50089040(CHEMBL17483 | N*2*,N*4*-Diphenyl-quinazoline-2,4-d...)Copy SMILESCopy InChI

Affinity DataIC50:  80nMAssay Description:Antagonistic activity against neuropeptide Y receptor type 5 subtype stably expressed in LM(tk-)cellsMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCruzipain(Trypanosoma cruzi)
Federal University Of Minas Gerais (Ufmg)

Curated by ChEMBL

LigandBDBM50089040(CHEMBL17483 | N*2*,N*4*-Diphenyl-quinazoline-2,4-d...)Copy SMILESCopy InChI

Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorometr...More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI