Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAminopeptidase N(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL

LigandBDBM50131539(CHEMBL3633447)Copy SMILESCopy InChI

Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of human recombinant aminopeptidase N using AbzdR-G-L-EDDnp as substrate after 20 to 40 mins by fluorometryMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNeprilysin(Homo sapiens (Human))
Institute Of Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL

LigandBDBM50131539(CHEMBL3633447)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant neutral endopeptidase using Ala-AMC as substrate after 20 to 40 mins by fluorometryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI