Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Astellas Pharma

US Patent

LigandBDBM284946(US10023583, Example 18)Copy SMILESCopy InChI

Affinity DataIC50:  2.60nMAssay Description:Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Astellas Pharma

US Patent

LigandBDBM284946(US10023583, Example 18)Copy SMILESCopy InChI

Affinity DataIC50:  7.90nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI