Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23821((2R)-2-amino-3-{[(4-bromophenyl)diphenylmethyl]sul...)
Affinity DataKi:  250nM ΔG°:  -37.7kJ/moleT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23821((2R)-2-amino-3-{[(4-bromophenyl)diphenylmethyl]sul...)
Affinity DataIC50:  26.8nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed