Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 18 hits in this display
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM408980(Thyroxine | US10377729, T4)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
IC50: 2.20E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
IC50: 4.90E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in bilirubin glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
IC50: 5.60E+3nMAssay Description:Inhibition of human recombinant UGT1A1 expressed in HEK293 cells assessed as reduction in estradiol 3-glucuronidation by LC-MS/MS methodMore data for this Ligand-Target Pair
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
IC50: 1.05E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
EC50: 1.00E+5nMAssay Description:Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysisMore data for this Ligand-Target Pair
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
BDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)