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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
28
hits in this display
Target
Glutamate receptor ionotropic, kainate 3
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
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Affinity Data
Ki: 1.74E+3nM
Assay Description:
Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cells
More data for this Ligand-Target Pair
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Target
Glutamate receptor ionotropic, kainate 1
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
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Affinity Data
Ki: 2.43E+3nM
Assay Description:
Displacement of [3H[SYM2081 from rat recombinant GluK1(Q)1b expressed in sS9 cells
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Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
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Affinity Data
Ki: 3.23E+3nM
Assay Description:
Displacement of [3H[SYM2081 from rat recombinant GluK2(VCR)a expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
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Target
Glutamate receptor 1
(Rattus norvegicus (Rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cells
More data for this Ligand-Target Pair
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Target
Glutamate receptor 4
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA4o expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
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Target
Glutamate receptor 3
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA3o expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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Target
Glutamate receptor 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA2(R)o expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Metabotropic glutamate receptor 1
(RAT)
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
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Affinity Data
EC50: 6.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR1c in rat
More data for this Ligand-Target Pair
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Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5.90E+5nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR4a in rat
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR5a in rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Metabotropic glutamate receptor 6
(Rattus norvegicus (Rat))
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
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Affinity Data
EC50: 1.00E+6nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR6 in rat
More data for this Ligand-Target Pair
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Target
Metabotropic glutamate receptor 3
(Rattus norvegicus (Rat))
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR3 in rat
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 1
(RAT)
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.30E+4nM
Assay Description:
Activity at rat cloned mGluR1a expressed in CHO cells assessed as effect on cAMP accumulation
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.10E+5nM
Assay Description:
Activity at rat cloned mGluR2 expressed in CHO cells assessed as effect on cAMP accumulation
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned mGluR4 expressed in CHO cells assessed as effect on cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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Copy BDB DOI
Target
Glutamate receptor 3
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR3 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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Ligand Info
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CHEMBL
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Article
PubMed
Copy BDB DOI
Target
Glutamate receptor 4
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR4 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR5 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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Ligand Info
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CHEMBL
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor 1
(Rattus norvegicus (Rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR1 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutamate receptor 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR2 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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Ligand Info
Purchase
CHEMBL
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 8
(Mus musculus)
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.50E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR2 in rat
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR5a in rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.00E+3nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR5b in rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(RAT)
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.00E+3nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR1a in rat
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
Università
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.00E+3nM
Assay Description:
Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
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CHEMBL
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(RAT)
Cns Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.40E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR1b in rat
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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CHEMBL
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