Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 36 hits in this display
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 1nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 13nMAssay Description:Inhibition of Syk (unknown origin) using 4 uM peptide assessed as product formation after 60 mins incubation by microfluidic mobility shift assayMore data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 13nMAssay Description:Inhibition of Syk (unknown origin) using 5-Fluo-Ahx-GAPDYENLQELNKK-Amide as substrate after 60 mins by microfluidic mobility shift assayMore data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 13nMAssay Description:Inhibition of Syk (unknown origin) using 5-Fluo-Ahx-GAPDYENLQELNKK-Amide as substrate after 60 mins by microfluidic mobility shift assayMore data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 60nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 81nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 123nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 139nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 166nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 199nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 244nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
IC50: 300nMAssay Description:Employing the Milipore panel of purified kinases EXAMPLE 87 (IC50=1 nM) inhibited 98% of purified Syk kinase activity at 50 nM. IC50 values were dete...More data for this Ligand-Target Pair
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)
BDBM50400047(BIIB-057 | CHEMBL2177736 | US9579320, Example 87)