Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331046(2-(2-(((5S,9S,12S)-12-amino-9-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331046(2-(2-(((5S,9S,12S)-12-amino-9-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331046(2-(2-(((5S,9S,12S)-12-amino-9-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  357nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in absence of 30 mM EDTA/600 uM 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331046(2-(2-(((5S,9S,12S)-12-amino-9-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  5.44E+3nMAssay Description:Inhibition of catalytic activity of human recombinant aminopeptidase N expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed