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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182797(US9145414, 160)
Affinity DataIC50:  0.380nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182797(US9145414, 160)
Affinity DataIC50:  1.30E+3nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibitory activity of the compound against Aurora B kinase activity was assayed with reference to a method described in patent publicat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182797(US9145414, 160)
Affinity DataIC50:  1.40E+3nMpH: 7.5Assay Description:Conditions for assaying the in vitro inhibitory activity of the compound against KDR kinase activity were set with reference to the statement in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent