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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 1.94nM
Assay Description:
Inhibition of human thrombin
More data for this Ligand-Target Pair
Target Info
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Ligand Info
CHEMBL
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Article
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PDB
3D Structure (crystal)
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Target
Coagulation factor X
(Homo sapiens (Human))
Philipps University Marburg
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 2.40nM
Assay Description:
Inhibition of factor 10a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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Article
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Target
Prothrombin
(Homo sapiens (Human))
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
Copy SMILES
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Affinity Data
Ki: 3.5nM
Assay Description:
Inhibition of thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PDB
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In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Plasma kallikrein
(Homo sapiens (Human))
Philipps University Marburg
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 8.30nM
Assay Description:
Inhibition of plasma kallikrein
More data for this Ligand-Target Pair
Target Info
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Target
Transmembrane protease serine 11D
(Homo sapiens (Human))
Philipps University Marburg
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 19nM
Assay Description:
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...
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Target Info
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KEGG
UniProtKB/SwissProt
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Target
Transmembrane protease serine 2
(Homo sapiens (Human))
Philipps University Marburg
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 20nM
Assay Description:
Inhibition of recombinant catalytic domain of TMPRSS2 expressed in Escherichia coli using Dcyclohexylalanine- Pro-Arg-AMC as substrate by fluorescenc...
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Plasminogen
(Homo sapiens (Human))
Philipps University Marburg
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 39nM
Assay Description:
Inhibition of plasmin
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Target Info
PDB
MMDB
NCI pathway
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KEGG
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Ligand Info
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Article
PubMed
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Target
Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human))
Philipps University Marburg
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 55nM
Assay Description:
Inhibition of matriptase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
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Article
PubMed
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Target
Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human))
Philipps University Marburg
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 55nM
Assay Description:
Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Transmembrane protease serine 6
(Homo sapiens (Human))
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
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Affinity Data
Ki: 170nM
Assay Description:
Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 mins
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transmembrane protease serine 6
(Homo sapiens (Human))
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 170nM
Assay Description:
Inhibition of matriptase 2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transmembrane protease serine 6
(Homo sapiens (Human))
University Of Bonn
Curated by
ChEMBL
Ligand
BDBM50324475
(Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 190nM
Assay Description:
Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 mins
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI